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Chromatographic instruments for ingredient fingerprint and component testing

ANALYTICAL TECHNOLOGY

Choose the method that answers the question.

Separate identity, fingerprint comparison and quantitative component testing.

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PROJECT FIT

Start by confirming whether this is the right route.

The technology is selected against the material, target specification, formula conditions and evidence needed.

WHAT IT CAN ADDRESS
  • Material identity
  • Marker-peak comparison
  • Fingerprint similarity
  • Qualitative profiling
  • Quantitative component testing
  • Third-party confirmation
APPLICABLE INGREDIENT TYPES
  • Multi-component botanical extracts
  • Standardized botanical ingredients
  • Defined single compounds
  • Project-specific investigative samples

CHALLENGE → TECHNICAL RESPONSE

Connect each project problem with a review action.

These are development routes, not universal performance claims. The applicable route is confirmed after reviewing the actual material and formula.

01
CUSTOMER CHALLENGE

Complex composition

One assay value may not represent a multi-component botanical material.

PINHONBIO APPROACH

Define the analytical question

Separate identity, qualitative profiling and quantitative testing.

02
CUSTOMER CHALLENGE

Method mismatch

A method may not be suitable for the analyte, matrix or decision.

PINHONBIO APPROACH

Select a suitable method

Choose HPLC, UPLC, GC, LC-MS, NMR, UV, HPTLC or IR according to the material.

03
CUSTOMER CHALLENGE

Disconnected reports

Samples, methods, standards and report numbers must remain traceable.

PINHONBIO APPROACH

Link the evidence

Connect sample identity, method, reference standard, data and report number.

DEVELOPMENT WORKFLOW

From requirement to reviewed sample.

  1. 01Analytical question
  2. 02Sample identity
  3. 03Method selection
  4. 04Testing
  5. 05Data review
  6. 06Report traceability

METHODS & SUPPORTING DATA

Verification follows the technical question.

01

HPTLC

Visual identity comparison for appropriate botanical materials.

02

HPLC / UPLC

Fingerprint, marker, assay or impurity analysis where method-suitable.

03

GC / GC-MS

Volatile, solvent or selected residue analysis.

04

UV / IR

Supporting identity or quantitative methods for suitable products.

05

LC-MS

Component confirmation, impurity review or investigative analysis for suitable samples.

06

NMR

Structural identity confirmation for suitable synthetic ingredients and defined compounds.

EVIDENCE & TECHNICAL BOUNDARIES

Know what the data supports—and what still needs validation.

Internal tests, third-party reports, typical data and customer-formula results must be identified separately.

Fingerprint scope

Primarily useful for suitable multi-component botanical materials.

Single compounds

Usually require identity, assay, purity and impurity methods instead.

Method suitability

No instrument is appropriate for every product or analytical question.

Typical data

Cannot be presented as the result of an untested batch.

Report traceability

Sample, method, date and report number must remain connected.

Typical or historical data do not replace the applicable batch COA. Finished-formula stability, compatibility, safety and claim substantiation remain the customer's responsibility unless separately agreed in writing.

PROJECT SUPPORT

Submit a technical request.

Share the ingredient, formula format, target pH, process, market and evidence needed.

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